I can say the both of mine sprung leaks(and burned/consumed more) with full syn, that didn't exist with traditional dino. Btw, the leaks also stopped back up when I switched back. YMMV as not all bikes will behave the same way. I think one large variable is the environment that you are/have been in and the condition of the seals.
I suppose with a fresh rebuild, new everything(seals, gaskets, etc) that full syn would be just fine.
I'm not starting an oil thread..... :yow just sharing my personal theory of the issue.